[gordguide]

You will probably want to use the Firewire port, if your destop supports it. Otherwise use USB.

Keep in mind that as per the USB spec, any single USB device is limited to 1/2 the bus's total speed (eg 6MB/sec for a 12MB/sec USB 1.1 port), something the USB 2 advocates conveniently forget when comparing to Firewire.