Sadly if Epson dont release a driver you prob wont get one, funny if you search for this printer some sites say its mac compatible. i see this all the time. I go through 3-4 printers a year, try their r200-r800 series. (You could always install it under virtualpc/windows but that is a sloppy way to get yer printing done)
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The Stylus C86 will be the new printer that was released for the Macintosh environment. It should be stressed that these decisions normally are made for many reasons at a much higher level but i am sure from the many conversations that i have had with Macintosh users that want more and advanced options and this lack of demand of entry-level inkjet printers in the Macintosh environment and the fact that they do the same thing except for the Stylus C86 is faster. It should be stressed that we pass the information as always to all outlets and provide them with the accurate information.
Unfortunately, there are no printer drivers for the Stylus C66 and Macintosh and will not be supported by Epson in a Macintosh environment. We are aware of many third-party printer driver companies that write drivers for our non-Macintosh printers, those third-party printer drivers are not support by Epson America.
I guess you could look for third-party drivers, but who knows how reliable those are. Apparently, the C-66 was replaced with the C-86, which, by the way, is a very good printer. Retails around $139, give or take some.
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Although it's a bit of a hassle to get going, there's a pretty good chance it's supported under CUPS (a UNIX app) which is included in OSX and which means you can probably get it to work.
The C66 isn't included with the OSX default install but the Gimp-Print package will install it (supposedly Gimp-Print was renamed to GutenPrint, but it apparently goes by both names).
The beta (v5x) has a C66 driver but you can also try the stable (v4x) release with the C64 driver, which is reported to work fine. I would try the beta since any bugs are printer-specific and chances are it will work fine, and the C66-specific driver has additional features you might want.