I decided a while back to no longer use adapters at all.
The extra two connectors are just two more potential trouble spots in the cable that I can do without.
I used to use a Mini-DVI to DVI adapter and then a DVI cable to connect one of my Minis,
But I had to prop theend of the adapter with the large DVI connector up so the adapter wouldn't loose the connection at the Mini-DVI port.
Instead of an adapter, I think the best way is to get a single cable with the appropriate connectors on each end.
For the scenario in this thread a Mini-DVI to DVI cable 3 to 6 ft long would be the right one (assuming the monitor has a regular DVI port, not a MIni-DVI port.
When I was googling to a cable like that I camer across an old thread on ehMac where I was looking for exactly that
Mini-DVI male to DVI male cable - 3 or 6ft long?
I received the cable but forgot to post a review or comments about it.
Well, there is really nothing to review - build quality was excellent, the white colour matches the Mini nicely, connectors fit nice and tight and I have been using it for two years it seems looking at the date of that thread and there is no problem - it just works like it should.
As far as I know, te cabling berween a Mini-DVI port and a DVI port is just wire, no signal conversion required.
The difference between Mini-DVI and DVI other than size is that Mini-DVI does not supprt dual link - thus the resolution limit I mentioned earlier.